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1

Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection

Stittelaar, Koert J., Neyts, Johan, Naesens, Lieve, van Amerongen, Geert, van Lavieren, Rob F., Holý, Antonin, De Clercq, Erik, Niesters, Hubert G. M., Fries, Edwin, Maas, Chantal

Journal:

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

2

Correlating process and product data to get an insight into translation difficulty

Vanroy, Bram, De Clercq, Orphée, Macken, Lieve

Journal:

Year:

2019

Language:

english

File:

PDF, 2.53 MB

english, 2019

3

Binomial sampling plan for tomato russet mite ( Aculopslycopersici (Tryon) (Acari: Eriophyidae) in protected tomato crops

Moerkens, Rob, Vanlommel, Wendy, Reybroeck, Eva, Wittemans, Lieve, De Clercq, Patrick, Van Leeuwen, Thomas, De Vis, Raf

Journal:

Journal of Applied Entomology

Year:

2018

Language:

english

File:

PDF, 848 KB

english, 2018

4

In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil

Pieter Annaert, Josef J. Tukker, Jan van Gelder, Lieve Naesens, Erik de Clercq, Guy van den Mooter, Renaat Kinget, Patrick Augustijns

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

5

The Validity of Cloninger's Psychobiological Model Versus the Five-Factor Model to Predict DSM-IV Personality Disorders in a Heterogeneous Psychiatric Sample: Domain Facet and Residualized Facet Descriptions

Filip De Fruyt, Barbara J. De Clercq, Lieve van de Wiele, Kees Van Heeringen

Journal:

Journal of Personality

Year:

2006

Language:

english

File:

PDF, 161 KB

english, 2006

6

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

Lieve Naesens, Chad E. Stephens, Graciela Andrei, Arianna Loregian, Leen De Bolle, Robert Snoeck, J. Walter Sowell, Erik De Clercq

Journal:

Antiviral Research

Year:

2006

Language:

english

File:

PDF, 323 KB

english, 2006

7

Mechanisms for the selective action of Vitamin D analogs

Roger Bouillon, Lieve Verlinden, Guy Eelen, Pierre De Clercq, Maurits Vandewalle, Chantal Mathieu, Annemieke Verstuyf

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 251 KB

english, 2005

8

Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts

Lieve Naesens, Pascale Bonnafous, Henri Agut, Erik De Clercq

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 572 KB

english, 2006

9

High population densities of Macrolophus pygmaeus on tomato plants can cause economic fruit damage: interaction with Pepino mosaic virus ?

Moerkens, Rob, Berckmoes, Els, Van Damme, Veerle, Ortega-Parra, Nelia, Hanssen, Inge, Wuytack, Martine, Wittemans, Lieve, Casteels, Hans, Tirry, Luc, De Clercq, Patrick, De Vis, Raf

Journal:

Pest Management Science

Year:

2016

Language:

english

File:

PDF, 462 KB

english, 2016

10

Multimodular Text Normalization of Dutch User-Generated Content

Schulz, Sarah, Pauw, Guy De, Clercq, Orphée De, Desmet, Bart, Hoste, Véronique, Daelemans, Walter, Macken, Lieve

Journal:

ACM Transactions on Intelligent Systems and Technology

Year:

2016

Language:

english

File:

PDF, 267 KB

english, 2016

11

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.

Saboulard, Didier, Naesens, Lieve, Cahard, Dominique, Salgado, Antonio, Pathirana, Ranjith, Velazquez, Sonsoles, McGuigan, Christopher, {De Clercq}, Erik, Balzarini, Jan

Journal:

Molecular Pharmacology

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

12

Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine]

Snoeck, Robert, Wellens, Willy, Desloovere, Christian, Ranst, Mark Van, Naesens, Lieve, De Clercq, Erik, Feenstra, Louw

Journal:

Journal of Medical Virology

Year:

1998

Language:

english

File:

PDF, 234 KB

english, 1998

13

ChemInform Abstract: Alkoxy-5-nitrosopyrimidines: Useful Building Block for the Generation of Biologically Active Compounds.

Antonio Marchal, Manuel Nogueras, Adolfo Sanchez, John N. Low, Lieve Naesens, Erik De Clercq, Manuel Mulguizo

Journal:

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010

14

Development of Analogues of 1α,25-Dihydroxyvitamin D3 with Biased Side-Chain Orientation: C20 Methylated Des-C,D-homo Analogues

Freek Vrielynck, Dirk Van Haver, Maurits Vandewalle, Lieve Verlinden, Annemieke Verstuyf, Roger Bouillon, Gianluca Croce, Pierre De Clercq

Journal:

European Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 681 KB

english, 2009

15

Alkoxy-5-nitrosopyrimidines: Useful Building Block for the Generation of Biologically Active Compounds

Antonio Marchal, Manuel Nogueras, Adolfo Sánchez, John N. Low, Lieve Naesens, Erik De Clercq, Manuel Melguizo

Journal:

European Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 589 KB

english, 2010

16

Inhibitory effects of 9-(2-Phosphonylmethoxyethyl)adenine and 3′-azido-2′,3′-dideoxythymidine on tumor development in mice inoculated intracerebrally with moloney murine sarcoma virus

Jan Balzarini, Halina Sobis, Lieve Naesens, Michel Vandeputte, Erik De Clercq

Journal:

International Journal of Cancer

Year:

1990

Language:

english

File:

PDF, 509 KB

english, 1990

17

Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (pmea) in vivo increases when it is less frequently administered

Jan Balzarini, Lieve Naesens, Erik De Clercq

Journal:

International Journal of Cancer

Year:

1990

Language:

english

File:

PDF, 521 KB

english, 1990

18

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice

Johan Neyts, Jan Balzarini, Lieve Naesens, Erik de Clercq

Journal:

Journal of Medical Virology

Year:

1992

Language:

english

File:

PDF, 540 KB

english, 1992

19

Efficacy of oral 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the treatment of retrovirus and cytomegalovirus infections in mice

Lieve Naesens, Johan Neyts, Jan Balzarini, Antonin Holy, Ivan Rosenberg, Erik De Clercq

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 626 KB

english, 1993

20

Quantitative analysis of human herpesvirus 6 cell tropism

L. De Bolle, J. Van Loon, E. De Clercq, Lieve Naesens

Journal:

Journal of Medical Virology

Year:

2005

Language:

english

File:

PDF, 400 KB

english, 2005

21

Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis

Georges de Bilderling, Eddy Bodart, Georges Lawson, David Tuerlinckx, Marc Remacle, Lieve Naesens, Erik De Clercq, Robert Snoeck

Journal:

Journal of Medical Virology

Year:

2005

Language:

english

File:

PDF, 87 KB

english, 2005

22

Heterocyclic rimantadine analogues with antiviral activity

Grigoris Zoidis, Christos Fytas, Ioannis Papanastasiou, George B. Foscolos, George Fytas, Elizaveta Padalko, Erik De Clercq, Lieve Naesens, Johan Neyts, Nicolas Kolocouris

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

23

Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure

Rafał Gawin, Erik De Clercq, Lieve Naesens, Mariola Koszytkowska-Stawińska

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 279 KB

english, 2008

24

Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs

Pelayo Camps, María D. Duque, Santiago Vázquez, Lieve Naesens, Erik De Clercq, Francesc X. Sureda, Marta López-Querol, Antoni Camins, Mercè Pallàs, S. Radhika Prathalingam, John M. Kelly, Vanessa Rome

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 541 KB

english, 2008

25

Design and synthesis of 1,2-annulated adamantane piperidines with anti-influenza virus activity

Grigoris Zoidis, Nicolas Kolocouris, Lieve Naesens, Erik De Clercq

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 364 KB

english, 2009

26

Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines

María D. Duque, Pelayo Camps, Lenuta Profire, Silvia Montaner, Santiago Vázquez, Francesc X. Sureda, Jordi Mallol, Marta López-Querol, Lieve Naesens, Erik De Clercq, S. Radhika Prathalingam, John M. K

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 265 KB

english, 2009

27

Design and synthesis of bioactive adamantane spiro heterocycles

Nicolas Kolocouris, Grigoris Zoidis, George B. Foscolos, George Fytas, S. Radhika Prathalingham, John M. Kelly, Lieve Naesens, Erik De Clercq

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

28

Superagonistic Fluorinated Vitamin D3 Analogs Stabilize Helix 12 of the Vitamin D Receptor

Guy Eelen, Noelia Valle, Yoshiteru Sato, Natacha Rochel, Lieve Verlinden, Pierre De Clercq, Dino Moras, Roger Bouillon, Alberto Muñoz, Annemieke Verstuyf

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 447 KB

english, 2008

29

Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines

Grigoris Zoidis, Nicolas Kolocouris, John M. Kelly, S. Radhika Prathalingam, Lieve Naesens, Erik De Clercq

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

30

Synthesis of 22-oxaspiro[4.5]decane CD-ring modified analogs of 1α,25-dihydroxyvitamin D3

Frederik De Buysser, Lieve Verlinden, Annemieke Verstuyf, Pierre J. De Clercq

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 425 KB

english, 2009

31

Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8

Erik De Clercq, Lieve Naesens, Leen De Bolle, Dominique Schols, Ying Zhang, Johan Neyts

Journal:

Reviews in Medical Virology

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

32

Clinical features and treatment of adenovirus infections

Liesbeth Lenaerts, Erik De Clercq, Lieve Naesens

Journal:

Reviews in Medical Virology

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

33

The modulation of cell shape influences porcine preadipocyte differentiation

Christophe Boone, Lieve De Clercq, Francine Grégoire, Claude Remacle

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1999

Language:

english

File:

PDF, 488 KB

english, 1999

34

Synthesis of 1,2-annulated adamantane heterocycles: structural determination studies of a bioactive cyclic sulfite

Grigoris Zoidis, Dimitra Benaki, Vassilios Myrianthopoulos, Lieve Naesens, Erik De Clercq, Emmanuel Mikros, Nicolas Kolocouris

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 619 KB

english, 2009

35

(S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA]: a purine analogue with trypanocidal activity in vitro and in vivo

Ronald Kaminsky, Cecile Schmid, Yvonne Grether, Antonin HolY, Erik De Clercq, Lieve Naesens, Reto Brun

Journal:

Tropical Medicine & International Health

Year:

1996

Language:

english

File:

PDF, 674 KB

english, 1996

36

Cytostatic and Antiviral Activity Evaluations of Hydroxamic Derivatives of Some Non-steroidal Anti-inflammatory Drugs

Zrinka Rajic, Ivan Butula, Branka Zorc, Sandra Kraljevic Pavelic, Karlo Hock, Kresimir Pavelic, Lieve Naesens, Erik De Clercq, Jan Balzarini, Monika Przyborowska, Tadeusz Ossowski, Mladen Mintas

Journal:

Chemical Biology & Drug Design

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

37

Discovery of Dihydro-Alkyloxy-Benzyl-Oxopyrimidines as Promising Anti-Influenza Virus Agents

Mingyan Yu, Ailin Liu, Guanhua Du, Lieve Naesens, Evelien Vanderlinden, Erik De Clercq, Xinyong Liu

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 154 KB

english, 2011

38

The Biological Activity of Nonsteroidal Vitamin D Hormone Analogs Lacking Both the C- and D-Rings

Annemieke Verstuyf, Lieve Verlinden, Hugo Van Baelen, Katrien Sabbe, Chris D'Hallewyn, Pierre De Clercq, Maurits Vandewalle, Roger Bouillon

Journal:

Journal of Bone and Mineral Research

Year:

1998

Language:

english

File:

PDF, 226 KB

english, 1998

39

Biological Activity of CD-Ring Modified 1α,25-Dihydroxyvitamin D Analogues: C-Ring and Five-Membered D-Ring Analogues

Annemieke Verstuyf, Lieve Verlinden, Evelyne Van Etten, Ling Shi, Yusheng Wu, Chris D'Halleweyn, Dirk Van Haver, Gui-Dong Zhu, Yong-Jun Chen, Xiaoming Zhou, Mark R. Haussler, Pierre De Clercq, Maurits

Journal:

Journal of Bone and Mineral Research

Year:

2000

Language:

english

File:

PDF, 2.37 MB

english, 2000

40

Interaction of Two Novel 14-Epivitamin D3 Analogs with Vitamin D3 Receptor-Retinoid X Receptor Heterodimers on Vitamin D3 Responsive Elements

Lieve Verlinden, Annemieke Verstuyf, Marcus Quack, Mark Van Camp, Evelyne Van Etten, Pierre De Clercq, Maurits Vandewalle, Carsten Carlberg, Roger Bouillon

Journal:

Journal of Bone and Mineral Research

Year:

2001

Language:

english

File:

PDF, 1.31 MB

english, 2001

41

Inhibition of Intestinal Metabolism of the Antiviral Ester Prodrug bis(POC)-PMPA by Nature-Identical Fruit Extracts as a Strategy to Enhance Its Oral Absorption: An In Vitro Study

Jan Van Gelder, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget, Patrick Augustijns

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.09 MB

1999

42

Synthesis of Novel AZA-Analogues of Tiazofurin with 2-[5,5-bis(Hydroxymethyl)Pyrrolidin-2-yl] Framework as Sugar Mimic

Mironiuk-Puchalska, Ewa, Koszytkowska-Stawińska, Mariola, Sas, Wojciech, De Clercq, Erik, Naesens, Lieve

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 222 KB

english, 2012

43

Transport, Uptake, and Metabolism of the Bis(pivaloyloxymethyl)-Ester Prodrug of 9-(2- Phosphonylmethoxyethyl)Adenine in an In Vitro Cell Culture System of the Intestinal Mucosa (Caco-2)

Pieter Annaert, Renaat Kinget, Lieve Naesens, Erik de Clercq, Patrick Augustijns

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 491 KB

1997

44

Design and synthesis of bioactive 1,2-annulated adamantane derivatives

Zoidis, Grigoris, Tsotinis, Andrew, Kolocouris, Nicolas, Kelly, John M., Prathalingam, S. Radhika, Naesens, Lieve, De Clercq, Erik

Journal:

Organic & Biomolecular Chemistry

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

45

ChemInform Abstract: Synthesis of Novel Aza-Analogues of Tiazofurin with 2-[5,5-Bis(hydroxymethyl)pyrrolidin-2-yl] Framework as Sugar Mimic.

Ewa Mironiuk-Puchalska, Mariola Koszytkowska-Stawinska, Wojciech Sas, Erik De Clercq, Lieve Naesens

Journal:

Year:

2012

File:

PDF, 31 KB

2012

46

Gonads ofCarassius auratus(teleosts) in organ culture: A new technique and the effects of testosterone

Lieve de Clercq, Claude Remacle, Jean Demal

Journal:

In Vitro Cellular & Developmental Biology - Plant

Year:

1977

Language:

english

File:

PDF, 1.73 MB

english, 1977

47

Culture of endocrine pancreatic cells in protein-free, chemically defined media

Fabienne Kinard, Lieve de Clercq, Brigitte Billen, Brigitte Amory, Jules-Joseph Hoet, Claude Remacle

Journal:

In Vitro Cellular & Developmental Biology - Plant

Year:

1990

Language:

english

File:

PDF, 2.36 MB

english, 1990

48

Human herpesvirus 6 DNA polymerase: enzymatic parameters, sensitivity to ganciclovir and determination of the role of the A961V mutation in HHV-6 ganciclovir resistance

Leen De Bolle, Chaysavanh Manichanh, Henri Agut, Erik De Clercq, Lieve Naesens

Journal:

Antiviral Research

Year:

2004

Language:

english

File:

PDF, 269 KB

english, 2004

49

In Vivo Antiviral Activity of 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine and its Cyclic Form

Graciela Andrei, Marcela Krecmerová, Antonín Holý, Lieve Naesens, Johan Neyts, Jan Balzarini, Erik De Clercq, Robert Snoeck

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 85 KB

english, 2007

50

Synthesis and Antiviral Activity of 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine and its Ester Prodrugs

Marcela Krecmerova, Antonin Holy, Alois Piskala, Graciela Andrei, Robert Snoeck, Lieve Naesens, Johan Neyts, Jan Balzarini, Erik De Clercq

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 74 KB

english, 2007